The film follows Joe, a self-diagnosed nymphomaniac, who recounts her erotic experiences to Seligman, an older man who finds her beaten and bruised in an alley. The narrative explores Joe's complex and tumultuous sexual history, beginning with her early sexual experiences and continuing through various liaisons that reveal her struggle with love, desire, and guilt. As she delves deeper into her past, her stories reveal a complex interplay of pleasure and pain, all while Seligman listens and offers his philosophical perspectives on her experiences.